Masyudi, Anita Noviyanti, Muhammad Ridhwan, Salfauqi Nurman, Jailani, Armi, T.M. Rafsanjani, Said Usman, Muhammad Hanafiah, Marlina
Blumea balsamifera L. has long been used as traditional medicine by communities in Aceh, Indonesia and from various parts of the world. For generations, this plant has been believed to have properties to cure various diseases. The results of the GCMS analysis of B. balsamifera leaf from Aceh-Indonesia in the previous study contain various compounds for wound healing, including borneol, jasmoline, camphor, and caryophyllene. The present study aimed to analyze the antibacterial activity of B. balsamifera leaves from Aceh. The sample was taken from the village of Gunongpulo, South Aceh-Indonesia, and the extraction process was carried out using three different types of solvents: ethanol, ethyl acetate, and n-hexane. Three variations of the extract obtained were then tested for antibacterial against Staphylococcus aureus and Pseudomonas aeruginosa by analyzing the inhibitory of each extract. The results showed that the inhibition zone formed on S. aureus against ethanol extract was 2.4 mm, ethyl extract was 9.2 mm, and n-hexane extract was 2.3 mm. In comparison, the inhibition zone formed on P. aeruginosa against ethanol extract was 0 mm, ethyl extract was 9 mm, and n-hexane extract was 4.9 mm. Conclusion: B. balsamifera leaf extract from Aceh contains antibacterial, with the highest inhibition against S. aureus at 9.2 mm and Pseudomonas at 9.0 mm. It is recommended that in the process of extracting B. balsamifera leaves by maceration, the best solvent used is ethyl acetate. © 2023, Society for Indonesian Biodiversity. All rights reserved.
Department of Public Health, Faculty of Public Health, Universitas Serambi Mekkah, Jl. Unmuha, Batoh, Lueng Bata, Aceh, Banda Aceh, 23245, Indonesia; Department of Biologi, Universitas Serambi Mekkah, Jl. Unmuha, Batoh, Lueng Bata, Aceh, Banda Aceh, 23245, Indonesia; Department of Ship Engineering, Politeknik Pelayaran Malahayati, Jl. Laksamana Malahayati No.Km.19, Durung, Mesjid Raya, Aceh, Aceh Besar, 23381, Indonesia; Faculty of Medicine, Universitas Syiah Kuala, Jl. Teuku Nyak Arief No.441, Kopelma Darussalam, Syiah Kuala, Aceh, Banda Aceh, 23111, Indonesia; Laboratory of Parasitology, Faculty of Veterinary Medicine, Universitas Syiah Kuala, Jl. Teuku Nyak Arief No.441, Kopelma Darussalam, Syiah Kuala, Aceh, Banda Aceh, 23111, Indonesia; Faculty of Nursing, Universitas Syiah Kuala, Jl. Teuku Nyak Arief No.441, Kopelma Darussalam, Syiah Kuala, Aceh, Banda Aceh, 23111, Indonesia
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