Nancy Margarita Rehatta, Susilo Chandra, Djayanti Sari, Mayang Indah Lestari, Tjokorda Gde Agung Senapathi, Haizah Nurdin, Belindo Wirabuana, Bintang Pramodana, Adinda Putra Pradhana, Isngadi Isngadi, Novita Anggraeni, Kenanga Marwan Sikumbang, Radian Ahmad Halimi, Zafrullah Khany Jasa, Akhyar Hamonangan Nasution, Mochamat Mochamat, Purwoko Purwoko
Background: With the more advanced science in the field of medicine and disease management, the population of geriatric intensive care patients is increasing. The COVID-19 pandemic has impacted healthcare management around the globe, especially on critically-ill elderly patients. We aim to analyse the relationship between underlying illnesses, including COVID-19, and the survival rate of elderly patients who are treated in the intensive care setting. Methods: We conducted a prospective cohort study at 14 teaching hospitals for Anaesthesiology and Intensive Therapy Education in Indonesia. We selected all subjects with 60 years of age or older in the period between February to May 2021. Variables recorded included subject characteristics, comorbidities, and COVID-19 status. Subjects were followed for 30-day mortality as an outcome. We analysed the data using Kaplan-Meier survival analysis. Results: We recruited 982 elderly patients, and 728 subjects were in the final analysis (60.7% male; 68.0 ± 6.6 years old). The 30-day mortality was 38.6%. The top five comorbidities are hypertension (21.1%), diabetes (16.2%), moderate or severe renal disease (10.6%), congestive heart failure (9.2%), and cerebrovascular disease (9.1%). Subjects with Charlson’s Comorbidity Index Score > 5 experienced 66% death. Subjects with COVID-19 who died were 57.4%. Subjects with comorbidities and COVID-19 had lower survival time than subjects without those conditions (p < 0.005). Based on linear correlation analysis, the more comorbidities the geriatric patients in the ICU had, the higher chance of mortality in 30 days (p < 0.005, R coefficient 0.22). Conclusion: Approximately one in four elderly intensive care patients die, and the number is increasing with comorbidities and COVID-19 status. © 2022, The Author(s).
Department of Anaesthesiology and Reanimation, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Department of Anaesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia; Department of Anaesthesiology and Intensive Therapy, Faculty of Medicine Universitas Sriwijaya, Jenderal Sudirman Street KM. 3.5, South Sumatera, Palembang, 30126, Indonesia; Department of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Udayana, Denpasar, Indonesia; Department of Anaesthesiology and Intensive Care, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia; Department of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; Department of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Riau, Riau, Pekanbaru, Indonesia; Department of Anaesthesiology and Intensive Care, Faculty of Medicine, Universitas Lambung Mangkurat, Banjarmasin, Indonesia; Department of Anaesthesiology and Intensive Care, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia; Department of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia; Department of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia; Department of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia; Department of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Indonesia
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