Novina Rahmawati, Maimun Syukri, Darmawi Darmawi, Indra Zachreini, Utari Zulfiani, Muhammad Yusuf, Rinaldi Idroes
This study aimed to study the inhibition activity of lactic acid bacteria probiotics deriving from Acehnese fermented Etawa goat's milk (yogurt) against Streptococcus pyogenes bacterial infection in rats (Rattus norvegicus). Haematological analysis of the rats' blood was performed on the following parameters: platelets, leukocytes, lymphocytes, neutrophils, and monocytes, where the data were further processed using ANOVA and Duncan's test with a confidence level of 95% (0.05). The results revealed that administering yogurt containing probiotics could reduce infections in the throats of rats caused by S. pyogenes. Based on the haematology examination, the probiotic yogurt could maintain the number of platelets, leukocytes, lymphocytes, neutrophils, and monocytes. Statistical significance was obtained when the infected rats were administered with a ±1.00 mL/day dose for seven days of treatment (p<0.05). © 2022 Novina Rahmawati et al.
Graduate School of Mathematics and Applied Sciences, Universitas Syiah Kuala, Banda Aceh, 23111, Indonesia; Medical Faculty, Universitas Syiah Kuala, Banda Aceh, 23111, Indonesia; Faculty of Veterinary Medicine, Universitas Syiah Kuala, Banda Aceh, 23111, Indonesia; Medical Faculty, Universitas Malikussaleh, Aceh Utara, Indonesia; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Kopelma Darussalam, Banda Aceh, 23111, Indonesia; Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh, 23111, Indonesia
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