Ultrafiltration of α-lactalbumin protein: Acquaintance of the filtration performance by membrane structure and surface alteration

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Nasrul Arahman, Cut Meurah Rosnelly, Yusni Yusni, Afrillia Fahrina, Silmina Silmina, Aulia Chintia Ambarita, Muhammad Roil Bilad, Poernomo Gunawan, Saeid Rajabzadeh, Ryosuke Takagi, Hideto Matsuyama, Muhammad Aziz

2021 Polymers Vol. 13 Issue 21 Article Cited by 12 SDG 17SDG 3 Quartile

Abstract

α-Lactalbumin is an essential protein with multiple roles in physiological and the nu-tritional functionalities, such as diabetic prevention, blood pressure stabilization, and cancer cell inhibition. In the present work, polyethersulfone (PES)-based membranes were developed by incorporating Pluronic F127 and carbon nanotubes with single-and multi-walled dimensions (Sw-Cnts and Mw-Cnts) as additives. The resulting membranes were evaluated for use in the filtration of α-lactalbumin protein solution. Four series of membranes, including PES pristine membrane, were fabricated via the phase inversion process. The characteristics of the membrane samples were analyzed in terms of morphology, membrane surface hydrophilicity and roughness, and surface chemistry. The characterization results show that the incorporation of additive increased the surface wettability by reducing the surface water contact angle from 80.4◦ to 64.1◦ by adding F127 and Mw-Cnt additives. The highest pure water permeability of 135 L/(m2·h·bar) was also exhibited by the PES/F127/Mw-Cnt membrane. The performance of the modified membranes was clearly better than the pristine PSF for α-lactalbumin solution filtration. The permeability of α-lactalbumin solution increased from 9.0 L/(m2·h·bar) for the pristine PES membrane to 10.5, 11.0 and 11.5 L/(m2·h·bar) for membranes loaded with Pluronic F127, Sw-Cnts, and Mw-Cnts, respectively. Those increments corre-sponded to 17, 22, and 28%. Such increments could be achieved without altering the α-lactalbumin rejections of 80%. Remarkably, the rejection for the membrane loaded with Sw-Cnts even increased to 89%. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Affiliations

Department of Chemical Engineering, Universitas Syiah Kuala, Banda Aceh, 23111, Indonesia; Magister Program of Environmental Management, Universitas Syiah Kuala, Banda Aceh, 23111, Indonesia; Research Center for Environmental and Natural Resources, Universitas Syiah Kuala, Jl. Hamzah Fansuri, No. 4, Darussalam, Banda Aceh, 23111, Indonesia; Doctoral Program, School of Engineering, Universitas Syiah Kuala, Jl. Syeh A. Rauf, No. 7,, Banda Aceh, 23111, Indonesia; Department of Physiology, Universitas Syiah Kuala, Banda Aceh, 23111, Indonesia; Faculty of Integrated Technologies, Universiti Brunei Darussalam, Bandar Seri Begawan, BE1410, Brunei Darussalam; School of Chemical & Biomedical Engineering, Nanyang Technological University, Singapore, 627833, Singapore; Research Center for Membrane and Film Technology, Department of Chemical Science and Engineering, Kobe University, Rokkodai-Cho 1-1, Nadaku, Kobe, 657-0000, Japan; Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo, 153-8505, Japan

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