Chiaki Tanaka, Viqqi Kurnianda, Masaya Morita, Toshimasa Suzuka, Junichi Tanaka
A marine macrolide halichondramide (1) was used as the basis for several actin-related studies as: a medium for affinity chromatography for G-actin; derivatives targeting G-actin; and fluorescent derivatives for staining cellular actin. The binding affinity to G-actin of halishigamide A (6) and its epimer 7 was compared with that of 1, as well as determining the configuration at C-5 of 6 by applying chiral derivatizing method. © 2021 Phytochemical Society of Europe
Department of Chemistry, Biology and Marine Science, University of the Ryukyus, Senbaru 1, Nishihara, 903-0213, Okinawa, Japan; School of Pharmaceutical Sciences, Wakayama Medical University, 25-1 Shichibancho, Wakayama, Wakayama, 640-8156, Japan; Department of Marine Science, Faculty of Marine and Fisheries, Syiah Kuala University, Darussalam, Banda Aceh, 23111, Indonesia; Sesoko Station, Tropical Biosphere Research Center, University of the Ryukyus, Motobu, 905-0227, Okinawa, Japan
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