V. Mardina, Mastura, Hamdani, E. Sufriadi
This study evaluated antioxidant and cytotoxicity of methanol extract from flowers of Sphagneticola trilobata (L.) J.F. Pruski. Phytochemical Screening of the flowers exhibited the presence of alkaloid, flavonoid, phenol, saponin, steroid and absent of tannin. The flowers extract also showed good source of antioxidant with an IC50 value of 19.072 µg/ml which was categorized in the range of strong antioxidant activity (<150 ppm). Cytotoxic activity of the flowers against HeLa cell line was found to 331.287 (LC50) or 83% inhibition. The results might suggest/ support the flower of S,trilobata as source of natural antioxidant. However, further study about in vivo antioxidant and lethal dose of this sample are recommended. © 2020 IOP Conference Series: Materials Science and Engineering.
Biology Department, Faculty of Engineering, Samudra University, Kampus Unsam Meurandeh, Langsa, Aceh, 24415, Indonesia; Chemistry Education Department, Faculty of Teacher Training and Education, Samudra University, Kampus Unsam Meurandeh, Langsa, 24415, Indonesia; Mechanical Engineering Department, Faculty of Engineering, Universitas Syiah Kuala, Aceh, 2311, Indonesia; Chemistry Department, Faculty of Mathematics and Natural Science, Universitas Syiah Kuala, Aceh, 2311, Indonesia
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