V. Kurnianda, M.R. Ramadhan, S. Karina, S. Agustina, C. Octavina, M. Ulfah, F. Syahliza, S.B. Faradilla, D.F. Putra, S. Purnawan, M. Musman
The investigation of bioactive compound from Indonesian marine sponge Petrosia sp. has been done on February 2019. The bioactive compound isolated based on bioassay-guide dseparation with several steps of chromatography. The bioactive compound known as C16H25NS determined by LCMS-ESI with molecular weight [M+H] + 263.42 m/z. The FTIR spectrumshowd that the bioactive metabolite has alkane skeleton of hydrocarbonat 2982.58 cm-1andisonitrile functional group at 2115 cm-1. The result of NMR interpretation showed that the bioactive compound know as 4-amorphene with decalin as hydrocarbon skeleton with additional isonitrile moiety. The rate of viability show scytotoxic against NBT-T2 cell. © Published under licence by IOP Publishing Ltd.
Department of Marine Science, Faculty of Marine and Fisheries, Syiah Kuala University, Banda Aceh, 23111, Indonesia; Department of Aquaculture, Faculty of Marine and Fisheries, Syiah Kuala University, Banda Aceh, 23111, Indonesia; Department of Chemistry Education, Faculty of Teacher Training and Education, Syiah Kuala University, Banda Aceh, 23111, Indonesia; Laboratory of Marine Chemistry and Fisheries Biotechnology, Faculty of Marine and Fisheries, Syiah Kuala University, Banda Aceh, 23111, Indonesia; Department of Chemistry, Faculty of Science, University of the Ryukyus, Nishihara, Okinawa, 903-0213, Japan
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