C.A. Nuraskin, Marlina, R. Idroes, C. Soraya, Djufri
People in Aceh, especially in the area of Ie Seu'um using the surrounding plants to treat diseases. One of the medical plants is laban (Vitex pinnata). Laban leaves are used to treat fever, hypertension, and toothache. Various bacteria found in the oral cavity, but only a few bacteria cause dental caries, including S. mutans Based on the laban plant ethnobotany information, an evaluation of antibacterial activity on bacterial bioindicator of S. mutans and phytochemical screening had been performed. Laban plants contain flavonoids, saponins, and tannins. This study aims to determine the inhibition activity of laban leaf methanol extract (Vitex pinnata) on the growth of S. mutans bacteria in vitro. The antimicrobacterial activity was tested by using the Kirby-Bauer method with the extract concentration of 30%, 40%, 50% and 60%. The results showed that there was an inhibition activity with the significance of 0.000 < 0.05, therefore the hypothesis in this research can be accepted that Laban leaf methanol extract (Vitex pinnata) has inhibition activity, the higher the concentration the higher inhibition power. © Published under licence by IOP Publishing Ltd.
Graduate School of Mathematics and Applied Sciences, Syiah Kuala University, Kopelma Darussalam, Banda Aceh, 23111, Indonesia; Poltekkes Kemenkes Aceh Jl. Soekarno Hatta, Tingkeum Darul Imarah, Lheu Blang, Banda Aceh, Kabupaten Aceh Besar, Aceh, 23231, Indonesia; Chemistry Department, Faculty of Mathematics and Natural Sciences, Syiah Kuala University, Kopelma Darussalam, Banda Aceh, 23111, Indonesia; Pharmacy Department, Faculty of Mathematics and Natural Sciences, Syiah Kuala University, Kopelma Darussalam, Banda Aceh, 23111, Indonesia; Conservative Dentistry Department, Faculty of Dentistry, Syiah Kuala University, Kopelma Darussalam, Banda Aceh, 23111, Indonesia; Biology Education Department, Faculty of Teacher Training and Education, Syiah Kuala University, Kopelma Darussalam, Banda Aceh, 23111, Indonesia
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