Herlina Dimiati, Abdus Samik Wahab, Mohammad Juffrie, Madarina Julia, Basri A. Gani
The Protein Energy Malnutrition (PEM) is the condition of a lack of carbohydrate and protein stores in the body that trigger chronic failure nutrient intake and body maintenance function caused to impact the heart functions. The NT-pro-BNP and HsTroponin I proteins were found as the indicator of cardiac dysfunction. The sixty subjects of PEM, analyzed by standard of Indonesia Healt Ministry as well as nutritional status. The blood electrolytes examined by laboratory assay and the levels of Hs-Troponin 1 and NT-Pro-BNP were analyzed by Immune-Chromatography method. Assessing of the ventricular mass with the seeing the peak of the diastolic flow rate of left ventricular that estimated by the curve of the receiver operating characteristic and the area under the curve (P<0.05). The result has shown that the PEM decreased in the left ventricular mass for impaired heart function and systolic disorder. The HsTroponin I (90.9%) has better sensitivity than NT-pro-BNP (85.5%) if the merger of those markers possesses the lowest sensitivity (81.8%). These proteins have good biomarkers in heart function, mainly in cases where PEM is present. © Copyright H. Dimiati et al., 2019 Licensee PAGEPress, Italy
Cardiology Division, Pediatric Health Department, Faculty of Medicine, Universitas Syiah Kuala-RSUZA Hospital, Banda Aceh, Indonesia; Pediatric Health Department, Faculty of Medicine, Gadjah Mada University, Yogyakarta, Indonesia; Oral Biology Department, Faculty of Dentistry, Universitas Syiah Kuala, Darussalam Banda Aceh, Indonesia
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