Unusual presentation of sheehan’s syndrome with severe hyponatremia and recurrent symptomatic hypoglycemia: A case report

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Siti Adewiah, Abdullah, Maimun Syukri, Hendra Zufry, Krishna Wardhana Sucipto

2016 Journal of the ASEAN Federation of Endocrine Societies Vol. 31 Issue 2 Article Cited by 3 SDG 3SDG 17 Quartile

Abstract

Sheehan’s syndrome (SS) is postpartum hypopituitarism caused by necrosis of the pituitary gland. The onset in most cases is several months or even years after the inciting delivery, so it is often unrecognized and not adequately treated. Because SS often evolves slowly, it is usually diagnosed late. We report a 47-year old woman with loss of consciousness. Fourteen years ago, she had postpartum hemorrhage with subsequent amenorrhea and failure to lactate. Laboratory investigation showed low blood sugar and serum sodium levels, amid normal cortisol and thyroid function tests. Magnetic resonance imaging (MRI) of the pituitary revealed an empty sella consistent with SS. The presentation of hypoglycemia and hyponatremia are less known complications of Sheehan’s syndrome with only a few documented in case reports. © 2016 by the JAFES.

Affiliations

Department of Internal Medicine, Faculty of Medicine, University of Syiah Kuala, Indonesia; Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine, University of Syiah Kuala/Zainoel Abidin Centre Hospital, Banda Aceh, Indonesia; Division of Endocrinology, Metabolism and Diabetes, Thyroid Center, Department of Internal Medicine, Faculty of Medicine, University of Syiah Kuala/Zainoel Abidin Centre Hospital, Banda Aceh, Indonesia

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